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Abnormal negative emotional state

MedGen UID:
1613560
•Concept ID:
C4531100
•
Mental or Behavioral Dysfunction
Synonym: Negative affectivity
 
HPO: HP:0031467

Definition

An aversive emotional state characterized by negative emotional experiences, preoccupations, or internal states that are often related to negative perceptions of the self, the world, or the future. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal negative emotional state

Professional guidelines

PubMed

Patterns of anxiety and distress over 12 months following participation in HPV primary screening.
Marlow LAV, McBride E, Ridout D, Forster AS, Kitchener H, Waller J
Sex Transm Infect 2022 Jun;98(4):255-261. Epub 2021 Aug 3 doi: 10.1136/sextrans-2020-054780. PMID: 34344834Free PMC Article
Differential neural reward mechanisms in treatment-responsive and treatment-resistant schizophrenia.
Vanes LD, Mouchlianitis E, Collier T, Averbeck BB, Shergill SS
Psychol Med 2018 Oct;48(14):2418-2427. Epub 2018 Feb 14 doi: 10.1017/S0033291718000041. PMID: 29439750Free PMC Article
Remodeling of axo-spinous synapses in the pathophysiology and treatment of depression.
Licznerski P, Duman RS
Neuroscience 2013 Oct 22;251:33-50. Epub 2012 Oct 2 doi: 10.1016/j.neuroscience.2012.09.057. PMID: 23036622Free PMC Article

Recent clinical studies

Etiology

Resting-state functional connectivity of the cerebellum-cerebrum in older women with depressive symptoms.
Feng L, Wu D, Ma S, Dong L, Yue Y, Li T, Tang Y, Ye Z, Mao G
BMC Psychiatry 2023 Oct 10;23(1):732. doi: 10.1186/s12888-023-05232-7. PMID: 37817133Free PMC Article
Relationship of stress-reactive cortisol to suicidal intent of prior attempts in major depression.
Herzog S, Galfalvy H, Keilp JG, Mann JJ, Sublette ME, Burke A, Oquendo MA, Stanley BH
Psychiatry Res 2023 Sep;327:115315. Epub 2023 Jun 24 doi: 10.1016/j.psychres.2023.115315. PMID: 37542793Free PMC Article
Cognitive deficits in bipolar disorders: Implications for emotion.
Lima IMM, Peckham AD, Johnson SL
Clin Psychol Rev 2018 Feb;59:126-136. Epub 2017 Nov 21 doi: 10.1016/j.cpr.2017.11.006. PMID: 29195773Free PMC Article
Large-Scale Network Dysfunction in Major Depressive Disorder: A Meta-analysis of Resting-State Functional Connectivity.
Kaiser RH, Andrews-Hanna JR, Wager TD, Pizzagalli DA
JAMA Psychiatry 2015 Jun;72(6):603-11. doi: 10.1001/jamapsychiatry.2015.0071. PMID: 25785575Free PMC Article
Effects of vitamin B12 and folate deficiency on brain development in children.
Black MM
Food Nutr Bull 2008 Jun;29(2 Suppl):S126-31. doi: 10.1177/15648265080292S117. PMID: 18709887Free PMC Article

Diagnosis

The Patient Experience After Spontaneous Coronary Artery Dissection.
Turner EA, Ivynian SE, Hickman L, DiGiacomo M
Heart Lung Circ 2023 Dec;32(12):1426-1433. Epub 2023 Nov 28 doi: 10.1016/j.hlc.2023.09.023. PMID: 38030470
Progesterone, reproduction, and psychiatric illness.
Standeven LR, McEvoy KO, Osborne LM
Best Pract Res Clin Obstet Gynaecol 2020 Nov;69:108-126. Epub 2020 Jun 18 doi: 10.1016/j.bpobgyn.2020.06.001. PMID: 32723604Free PMC Article
Cognitive deficits in bipolar disorders: Implications for emotion.
Lima IMM, Peckham AD, Johnson SL
Clin Psychol Rev 2018 Feb;59:126-136. Epub 2017 Nov 21 doi: 10.1016/j.cpr.2017.11.006. PMID: 29195773Free PMC Article
Effects of Anorexia Nervosa on the Endocrine System.
Baskaran C, Misra M, Klibanski A
Pediatr Endocrinol Rev 2017 Mar;14(3):302-311. doi: 10.17458/per.vol14.2017.BMK.effectsanorexianervosa. PMID: 28508601
Psychosis.
Arciniegas DB
Continuum (Minneap Minn) 2015 Jun;21(3 Behavioral Neurology and Neuropsychiatry):715-36. doi: 10.1212/01.CON.0000466662.89908.e7. PMID: 26039850Free PMC Article

Therapy

Associations between abnormal electroencephalogram microstates and childhood emotional abuse in adolescent depression.
Hu J, Zhou D, Zhao L, Ma L, Peng X, He X, Chen R, Chen W, Jiang Z, Kuang L, Wang W
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2023 Nov 28;48(11):1678-1685. doi: 10.11817/j.issn.1672-7347.2023.230220. PMID: 38432858Free PMC Article
Behavioural and emotional implications of implantable cardioverter-defibrillators in the young and in athletes.
Dechert BE
Cardiol Young 2017 Jan;27(S1):S138-S142. doi: 10.1017/S1047951116002389. PMID: 28084974
Psychosis.
Arciniegas DB
Continuum (Minneap Minn) 2015 Jun;21(3 Behavioral Neurology and Neuropsychiatry):715-36. doi: 10.1212/01.CON.0000466662.89908.e7. PMID: 26039850Free PMC Article
Neuropsychological mechanism underlying antidepressant effect: a systematic meta-analysis.
Ma Y
Mol Psychiatry 2015 Mar;20(3):311-9. Epub 2014 Mar 25 doi: 10.1038/mp.2014.24. PMID: 24662929
Effects of vitamin B12 and folate deficiency on brain development in children.
Black MM
Food Nutr Bull 2008 Jun;29(2 Suppl):S126-31. doi: 10.1177/15648265080292S117. PMID: 18709887Free PMC Article

Prognosis

Psychiatric and affective predictors of negative racial attitudes.
Kimhy D, Ospina LH, Beck-Felts K, Lister A, Omene C, Bodenhausen G, Mittal V
Psychiatry Res 2023 Sep;327:115376. Epub 2023 Jul 30 doi: 10.1016/j.psychres.2023.115376. PMID: 37531817
Reward Processing in Adolescent Depression Across Neuroimaging Modalities.
O'Callaghan G, Stringaris A
Z Kinder Jugendpsychiatr Psychother 2019 Nov;47(6):535-541. Epub 2019 Apr 8 doi: 10.1024/1422-4917/a000663. PMID: 30957688Free PMC Article
Abnormal cortical gyrification in criminal psychopathy.
Miskovich TA, Anderson NE, Harenski CL, Harenski KA, Baskin-Sommers AR, Larson CL, Newman JP, Hanson JL, Stout DM, Koenigs M, Shollenbarger SG, Lisdahl KM, Decety J, Kosson DS, Kiehl KA
Neuroimage Clin 2018;19:876-882. Epub 2018 Jun 6 doi: 10.1016/j.nicl.2018.06.007. PMID: 29946511Free PMC Article
Cognitive deficits in bipolar disorders: Implications for emotion.
Lima IMM, Peckham AD, Johnson SL
Clin Psychol Rev 2018 Feb;59:126-136. Epub 2017 Nov 21 doi: 10.1016/j.cpr.2017.11.006. PMID: 29195773Free PMC Article
Depression in Parkinson's disease.
Burn DJ
Eur J Neurol 2002 Nov;9 Suppl 3:44-54. doi: 10.1046/j.1468-1331.9.s3.6.x. PMID: 12464121

Clinical prediction guides

Theory of mind in epilepsy.
Watanabe RGS, Thais MERO, Marmentini EL, Freitas TG, Wolf P, Lin K
Epilepsy Behav 2024 Sep;158:109910. Epub 2024 Jul 2 doi: 10.1016/j.yebeh.2024.109910. PMID: 38959746
Resting-state functional connectivity of the cerebellum-cerebrum in older women with depressive symptoms.
Feng L, Wu D, Ma S, Dong L, Yue Y, Li T, Tang Y, Ye Z, Mao G
BMC Psychiatry 2023 Oct 10;23(1):732. doi: 10.1186/s12888-023-05232-7. PMID: 37817133Free PMC Article
Relationship of stress-reactive cortisol to suicidal intent of prior attempts in major depression.
Herzog S, Galfalvy H, Keilp JG, Mann JJ, Sublette ME, Burke A, Oquendo MA, Stanley BH
Psychiatry Res 2023 Sep;327:115315. Epub 2023 Jun 24 doi: 10.1016/j.psychres.2023.115315. PMID: 37542793Free PMC Article
Reward Processing in Adolescent Depression Across Neuroimaging Modalities.
O'Callaghan G, Stringaris A
Z Kinder Jugendpsychiatr Psychother 2019 Nov;47(6):535-541. Epub 2019 Apr 8 doi: 10.1024/1422-4917/a000663. PMID: 30957688Free PMC Article
Cognitive deficits in bipolar disorders: Implications for emotion.
Lima IMM, Peckham AD, Johnson SL
Clin Psychol Rev 2018 Feb;59:126-136. Epub 2017 Nov 21 doi: 10.1016/j.cpr.2017.11.006. PMID: 29195773Free PMC Article

Recent systematic reviews

Psychological and Behavioral Impact of Lockdown and Quarantine Measures for COVID-19 Pandemic on Children, Adolescents and Caregivers: A Systematic Review and Meta-Analysis.
Panda PK, Gupta J, Chowdhury SR, Kumar R, Meena AK, Madaan P, Sharawat IK, Gulati S
J Trop Pediatr 2021 Jan 29;67(1) doi: 10.1093/tropej/fmaa122. PMID: 33367907Free PMC Article
The Impact of Communication Surrounding Intrauterine Congenital Anomaly Diagnoses: An Integrative Review.
Berry SN, Colorafi K
J Perinat Neonatal Nurs 2019 Oct/Dec;33(4):301-311. doi: 10.1097/JPN.0000000000000390. PMID: 30741752
'Hot' cognition in major depressive disorder: a systematic review.
Miskowiak KW, Carvalho AF
CNS Neurol Disord Drug Targets 2014;13(10):1787-803. doi: 10.2174/1871527313666141130205713. PMID: 25470389
Mobile phone messaging for communicating results of medical investigations.
Gurol-Urganci I, de Jongh T, Vodopivec-Jamsek V, Car J, Atun R
Cochrane Database Syst Rev 2012 Jun 13;2012(6):CD007456. doi: 10.1002/14651858.CD007456.pub2. PMID: 22696369Free PMC Article

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